Into liquid purification enrichment method? Ultrafiltration purification

Membrane separation process is mainly divided into microfiltration, ultrafiltration, nanofiltration, reverse osmosis and electrodialysis process. Because of effective ingredients of Chinese herbal medicine under 1000, molecular weight and molecular weight of up to tens of thousands to hundreds of thousands of invalid ingredients, very suitable for separation and purification by ultrafiltration, also suitable for using nanofiltration technology to traditional Chinese medicine (TCM) for enrichment, attain the goal of saving energy and improving product quality.

the ultrafiltration technology can filter out water extract or alcohol extract of Chinese medicine relative molecular mass is greater than the tens of thousands of ineffective ingredients, such as cellulose, phlegmatic, gum, starch, tannins, proteins ( Except a few herbs) , resin, etc. , such as traditional Chinese medicine effective parts extracted with the use of ultrafiltration and effective ingredients, such as radix scutellariae, active polysaccharide, Oriental arborvitae 6 flavour glutinous rehmannia flavonoids, etc. Ultrafiltration technology is widely used in the preparation of traditional Chinese medicine injection, if use two steps common clubmoss herb injection preparing ultrafiltration membrane, the molecular weight of 10000 ~ 30000 ultrafiltration membranes were used to remove macromolecule material, using 6000 intercept molecular weight of ultrafiltration membrane to remove small molecular impurities and join in the process of preparation of sodium chloride. Preparation of injection, the high rate, good clarity, sodium chloride content decreased from 5% to 1%, the process is simple, easy to mass production. In traditional Chinese medicine oral liquid preparation of Chinese super filter technology is also widely used, such as in pulse-activating decoction oral liquid, ultrafiltration method of water extract-alcohol precipitation and the method compared with the total solid improve 51. 83%; Flavonoids increased 23. 40%, the total polysaccharides by 90. 08%; The total organic acids improve 8. 03%; (the original process changed from brown to light brown color, Water extraction method) and ethyl alcohol deposition. then Production of pulse-activating decoction oral liquid storage of 6 months namely, precipitation and the new process ( Ultrafiltration method) Production of pulse-activating decoction oral liquid is placed after 18 months is still clear. Need to use a lot of alcohol in the original production technology, and with special equipment for recycling of alcohol, not only the equipment investment is large, and the amount of alcohol consumption in more than 30%, seriously polluted the environment, and the new technology does not exist the shortcomings.

because of the effective ingredients of Chinese traditional medicine molecular weight is below 1000 commonly, suit to use nanofiltration enrichment. The traditional manual method of Chinese traditional medicine, such as multiple effect distillation has many disadvantages, high energy consumption, serious organic solvent loss and on water and air pollution is serious, the disadvantage of high effective ingredients loss. Nanofiltration is applied to the enrichment and separation of Chinese traditional medicine can effectively solve the above problems. The nanofiltration membrane to perform interesting no phase change, for some heat sensitive drugs in traditional Chinese medicine, such as saponins, steroid, terpenoids, etc. The separation and enrichment of more appropriate.

the nanofiltration membrane separation technology used in yunnan white soap glucoside of alcohol extraction liquid separation enrichment, nanofiltration can be through the liquid ( Alcohol) Directly used in the production process, due to the membrane separation system can realize closed cycle, ethanol consumption greatly reduced. , vacuum steam consumption is also reduced, simplify the production process, save, shorten production cycle, product quality is stable and improve; Using nanofiltration membrane separation technology used in traditional Chinese medicine (TCM) water extraction liquid separation enrichment, steam consumption reduction, greatly shorten the production cycle, saving, through the liquid ( Water) Can consider to used in the production process, the quality of the products will be more stable and improve. A preliminary estimate, the alcohol consumption within a year to reduce the cost of the item can call in the investment cost of the equipment. To be stable at present the system running parameters meet the design requirements. In ginkgo biloba extract, puerarin, such as the production of traditional Chinese medicine, also successfully using nanofiltration to preconcentration, the material liquid concentrated more than 20 times, and then into the negative pressure three-way enrichment, realize the energy saving more than 80%, recovery of alcohol at the same time, the implementation of cleaner production.